Fosamax and The Risks It Brings

Fosamax is used to prevent bone loss problems in post-menopausal women experiencing a substantial decline of estrogen hormone production and who are at risk of a bone degenerative disease, medical journals say. It is also used to prevent and treat osteoporosis that is due to long-term use of corticosteroids such as prednisone. 

 

Fosamax generally works to slow down bone loss by increasing the bone mass naturally. It is applicable to both men and women, although bone degenerative diseases have been noted by medical researchers to be more prevalent in older women.

 

The brand name for alendronate sodium, Fosamax is a prescription drug that belongs to the family of bisphosphonates . Duly approved by the US Food and drug Administration (FDA), it was named one of the most prescribed bisphosphonates drug in the United States, with over 37 million written prescriptions for it by the year 2008 alone. However, alongside its  popularity in the medical world are controversies rooted on the many adverse events coming from its patrons linking Fosamax to certain diseases.

 

As for other drugs, Fosamax has been associated with many dangerous side effects.  Among the most serious are esophagitis and esophageal ulcers.  The patient using alendronate may experience irritation in the food pipe, difficulty swallowing and pain when swallowing. The irritation in the lining of the esophagus  is referred to as esophagitis.

 

Esophagitis and esophageal ulcer are the most commonly reported abnormalities linked to Fosamax use, according to researchers. In the evaluation entitled "Esophagitis Associated with the Use of Alendronate" published in The New England Journal of Medicine, Dr. Piet de Groen and colleagues reported that direct chemical injury of the esophagus uncommonly occurs with oral alendronate treatment. These side effects were noted with prolonged oral alendronate use but the same was not proven in terms of alendronate administered intravenously.

 

Other problems affecting the esophagus and related to Fosamax use are esophageal perforation and esophageal stricture. The former refers to a condition in which a hole is found in the food pipe. Research indicates that this is a rare condition. However,  it is serious and requires emergency treatment. The latter is a recurring episode of esophagitis or esophageal ulcers due to alendronate use that advances and creates scarring of the esophagus.  These Fosamax side effects comprise those risks affecting the esophagus only. There are more reports linking the use of this drug to other diseases that calls for a more in-depth study.

 

URL References:

  • livestrong.com/article/109091-dangerous-side-effects-fosamax/
  • osteoporosis.emedtv.com/fosamax/fosamax-side-effects-p2.html
  • nof.org/node/67

 

 



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